An audit on genitor-urinary malignancies in a specialist center in Sri Lanka.

Abstract

Introduction: Data regarding occurrence and relative frequency genitourinary malignancies(GUM) in Sri Lanka are sparse.

Method: A retrospective review of all patients with GUM managed at a specialized genitourinary surgical facility from January 2010 was performed. Relative frequency and demographic data of all cases were evaluated on the prospective clinical database.

Results: Over a period of 30 months there were 262 patients with GUM. 50.2% (128) had Prostate Carcinoma (PCa), 33.6% (87) bladder carcinoma of which 87.2 %( 75) were males and 12.8 %( 11) female. 16.2 %( 42) had renal cell carcinoma (RCC) of which 83.3% were male.There were only two testicular cancers and one penile cancer.Mean age at the time of diagnosis of CaP was 70(range 52-91), 65 years for BCa (range 38-88) and 64 for RCC (range36-78). Majority of PCa patients (65.7%) had locally advanced or metastatic disease at presentation. 43% (55) had a PSA>40and 51.6% (66) had Gleason’s score 7-10 at presentation. Most of the Bladder Ca patients presented with macroscopic haematuria (81%) of which 93.3% were diagnostic on USS.70% (28) of the RCC patients had macroscopic haematuria and 60% (24) had palpable abdominal mass at presentation.

Conclusion: This audit highlights that most GU malignancies present at an advanced stage in our patients. The sparcity of penile and testicular cancers may be a result of referral patterns.A coordinated multicentre or national study at least among oncology and urology units is likely to produce valuable data to ascertain health care needs for GUM.