Duration of Diabetes and eGFR -A Preliminary Study

Abstract

Objective: The objective of this study was to assess whether there is a significant difference in duration of type 2 diabetes with estimated glomerular filtration rate (eGFR).

Method: A descriptive study was carried out using 67 patients with type 2 diabetes between the ages 30- 60 years attending the diabetic clinic of Colombo South Teaching Hospital. The 4 variable Modification of Diet in Renal Disease (MDRD) Study Equation was used to calculate the eGFR using the latest available serum creatinine levels.

Results: Total number of subjects in the study group was 67 with 11 males and 56 females. Among this diabetic population, 32 were having an eGFR in the range of 30 to 59 ml/min/1.732m2 while 35 had an eGFR in the range 60-89ml/min/1.732m2. Independent student t test values obtained by comparing the two groups showed no significant difference between the mean values and duration of diabetes mellitus (p>0.05).

Conclusions: According to this study, there was no significant difference in the duration (from the date of diagnosis) of diabetes mellitus between the eGFR 30 to 59 ml/min/1.732m2 (CKD stage 3 ) group and the eGFR more than 60ml/min/1.732m2 group. This highlights the importance of assessing renal functions early in newly diagnosed type 2 diabetics since early or late diagnosis of diabetes and its control from the day of diagnosis may be factors affecting the their renal functions (eGFR).